FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ewg11
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General Information
Symbol
Dmel\ewg11
Species
D. melanogaster
Name
FlyBase ID
FBal0003897
Feature type
allele
Associated gene
Dmel\ewg
Associated Insertion(s)
Carried in Construct
Also Known As
ewgl6
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(DeSimone et al., 1996)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Myoblasts are present, migrate normally and get distributed over the persistent thoracic larval muscles in animals expressing ewgelav.NS in an ewg11 background, but splitting of the persistent larval muscles does not occur in some genetic backgrounds. Fusion of the imaginal myoblasts with the larval muscles occurs normally, but the wild-type progressive alignment of fused myoblast nuclei into longitudinal columns does not occur in these animals.

      (Roy and VijayRaghavan, 1998)

      Lethality occurs during early embryo and larval stages. There are occasional adult escapers.

      (DeSimone et al., 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      ewg11 is rescued by ewgSC3ORF.elav

      (DeSimone et al., 1996)

      ewg11 is rescued by ewghs.PD

      (de Simone and White, 1993)
      Comments

      Lethality can be rescued by ewgelav.NS. Rescued adults do not exhibit an erect wing phenotype.

      (DeSimone et al., 1996)

      ewghs.PD rescues lethality associated with ewg11.

      (de Simone and White, 1993)

      ewg11 complements at least partially ewg4, ewg5, ewg10, and ewg12.

      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      White.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ewg11
      ewgl6
      (DeSimone et al., 1996, de Simone and White, 1993, Fleming et al., 1989)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)