FB2026_02 , released June 18, 2026
Allele: Dmel\bbflex-1
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General Information
Symbol
Dmel\bbflex-1
Species
D. melanogaster
Name
FlyBase ID
FBal0004021
Feature type
allele
Associated gene
bb
Associated Insertion(s)
Carried in Construct
Also Known As
flex1
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Bhattacharya et al., 1999)
Mutagen
ethyl methanesulfonate
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Lethal to males in the absence of a Y chromosome. Recessive lethal in XX females.

      (Cline, 2001)

      Hemizygous males show the same viability as the non-bbflex-1 siblings. Recessive lethality acts primarily at the embryonic stage with some individuals reaching the first instar larval stage.

      (Bhattacharya et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      Df(YS)bb, bbflex-1 has lethal | male phenotype

      (Cline, 2001)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      bbflex-1 is male lethal over the Df(YS)bb chromosome, which is Ybb-.

      (Cline, 2001)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      bbflex-1
      flex1
      (Cline, 2001, Bhattacharya et al., 1999)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)