FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\fliI8
Open Close
General Information
Symbol
Dmel\fliI8
Species
D. melanogaster
Name
FlyBase ID
FBal0004042
Feature type
allele
Associated gene
Dmel\fliI
Associated Insertion(s)
Carried in Construct
Also Known As
D44
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(de Couet et al., 1995)
Mutagen
MRh12 induced male recombination
(Eeken et al., 1985)
Progenitor genotype
Cytology
Description

Deletion of base pairs 233-624 in the 5' section of the fliI transcription unit. This deletes sequences from 207bp upstream of the presumed transcription initiation site, including the translational start site at position 505, and 66 bases of the first intron. The 5' flanking sequence AAACC at the deletion site is duplicated twice in the deletion, suggesting the deficiency may have arisen as a consequence of a transposition event.

(de Couet et al., 1995)

Small deficiency within the fliI locus.

(Campbell et al., 1993)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
X:21,339,629..21,340,013 [+]
Comment:

A 384bp deletion which removes the translation start codon. There is also a 10bp insertion (two copies of the 5' flanking sequence AAACC) at the site of the deletion. Position of mutation on reference sequence inferred by FlyBase curator based on author statement (Figures 3 and 4).

Inserted_sequence:

AAACCAAACC

(de Couet et al., 1995)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      (1)ESHS531
      D44
      (Campbell et al., 1993, Eeken et al., 1985)
      fliD44
      (Perrimon et al., 1989)
      fliI8
      l(1)D44
      (de Couet et al., 1995)
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0007585
      References (4)