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General Information
Symbol
Dmel\fz13
Species
D. melanogaster
Name
FlyBase ID
FBal0004929
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
fzF31
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Nucleotide change:

C14311900T

Reported nucleotide change:

C?T

Amino acid change:

P278S | fz-PA; P278S | fz-PC

Reported amino acid change:

P278S

Comment:

P278 is in the first cytoplasmic loop of the fz protein.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: P278S.

Mutation is in the first cytoplasmic loop of the fz protein.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

fz13 has a weak multiple wing hair phenotype in combination with fz30.

Autonomous phenotype in wing clones.

eye texture normal causes severe disruption of trichome orientation in the costal wing cell, a region little affected by most alleles; phenotype of homozygote more severe than that of hemizygote. Also unlike other alleles, homozygous clones of fz13 cells in the wing do not affect orientation of trichomes in surrounding normal cells. A third notable feature of fz13 is that it is without effect on eye texture. moderate thoracic bristle phenotype moderate wing-hair disorientation

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference
Phenotype Manifest In
Suppressor of
Statement
Reference

fz[+]/fz13 is a suppressor of ommatidium phenotype of Scer\GAL4hs.2sev, dgoUAS.cFa

Additional Comments
Genetic Interactions
Statement
Reference

The planar cell polarity defects seen in the eyes of flies expressing dgoScer\UAS.cFa under the control of Scer\GAL4hs.2sev are dominantly suppressed by fz13/+.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Adler.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
References (10)