FB2026_02 , released June 18, 2026
Allele: Dmel\gtE6
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General Information
Symbol
Dmel\gtE6
Species
D. melanogaster
Name
FlyBase ID
FBal0005237
Feature type
allele
Associated gene
Dmel\gt
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Judd et al., 1972)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      gtE6 larvae exhibit a prolonged third instar stage in 25% of females and 13% of male animals. Larvae and pupae are significantly larger than control animals.

      (Ghosh et al., 2010)

      gtQ292/gtE6 larvae synthesise DNA of a reduced molecular weight, have an unusually high frequency of spontaneous single and double-strand breaks, and shows a reduction in the normal inhibition of DNA synthesis following treatment with UV.

      (Narachi and Boyd, 1985)

      Greatly reduced viability of heterozygotes with Df(1)w-rJ1.

      (Lim and Snyder, 1974)

      Larval development is extended by 4-5 days, polytene chromosomes undergo additional replication and larval, pupal and imago size is increased. Heterozygotes with Df(1)w-rJ1 have reduced viability and the few adult escapers have a normal phenotype.

      (Judd et al., 1972)

      viable-low penetrance

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      Kaufman.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      gtE6
      (Ghosh et al., 2010)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)