FB2026_03 , released September 17, 2026
Allele: Dmel\haync2rv4
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General Information
Symbol
Dmel\haync2rv4
Species
D. melanogaster
Name
FlyBase ID
FBal0005388
Feature type
allele
Associated gene
Dmel\hay
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

antimorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

antimorphic allele - genetic evidence

(Regan and Fuller, 1990)
Mutagen
ethyl methanesulfonate
(Regan and Fuller, 1990)
Progenitor genotype
haync2
(Mounkes et al., 1992, Regan and Fuller, 1990)
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      haync2/haync2rv4 animals show 12.4% viability. 47.9% of haync2/haync2rv4 adults have deformed and fragile macrochaetae and microchaetae, 16.6% have a reduction of the endocuticular layer of the abdominal cuticle and 0% show loss of wing marginal regions and blistered wings.

      (Merino et al., 2002)

      Lethal over deficiency of hay. Heterozygotes exhibit defects in the structure and function of the male meiotic spindle.

      (Regan and Fuller, 1990)

      recessive larval lethal

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      haync2rv4 is rescued by hayhs.P

      (Mounkes et al., 1992)
      Not rescued by

      haync2rv4 is not rescued by hayA17T,G23A

      (Mounkes et al., 1992)
      Comments

      Lethality and male sterility rescued by heat-shock of hsp70-hay construct.

      (Mounkes et al., 1992)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      haync2rv4
      Name Synonyms
      Secondary FlyBase IDs
        References (3)