FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\hop9
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General Information
Symbol
Dmel\hop9
Species
D. melanogaster
Name
FlyBase ID
FBal0005520
Feature type
allele
Associated gene
Dmel\hop
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Perrimon and Mahowald, 1986)
Mutagen
ethyl methanesulfonate
Progenitor genotype
Cytology

Polytene chromosomes normal.

(Perrimon and Mahowald, 1986)
Description

Amino acid replacement: G175R. The mutation is within the JH6 domain.

(Luo et al., 1999)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
X:11,366,940..11,366,940 [-]
Nucleotide change:

G11366940M

Amino acid change:

G175R | hop-PA

Reported amino acid change:

G175R

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Luo et al., 1999)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Paternal rescue of the maternal effect. Germline clone analysis demonstrates that embryos have one abdominal segment missing and A4 appears wider than wild type, and partial or complete fusion of T1 and T2.

      (Perrimon and Mahowald, 1986)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Lefevre.

      Comments
      Comments

      Fail to complement hop25.

      (Perrimon and Mahowald, 1986)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      DC764
      (Luo et al., 1999)
      hop9
      l(1)DC764
      l(1)hopDC764
      (Perrimon and Mahowald, 1986)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)