Time to eclosion in homozygotes is 4-7 days longer than wild-type flies at room temperature.

kdn^PG129-R1/kdn^PC64 and kdn^KG04873-R1/kdn^PC64 flies do not show bang sensitivity.

The giant fiber(GF)-dorsal longitudinal indirect flight muscle (DLM) neuronal circuit is more sensitive to seizure induction in kdn^PC64/kdn^PG129 mutants than in wild-type flies; seizures can be induced with high-frequency brain stimulation of shorter or less intensity in the mutant animals. The mutant animals show type I seizures.

Bang-sensitive mutant. Flies usually show abnormal spontaneous activity ("seizures") in the dorsal longitudinal muscle (DLM) lasting approximately 0.5-3 seconds after the delivery of an electrical buzz (50-400 msec) to the brain. Stimulation of the giant fibre (GF) usually fails to evoke DLM potentials following the buzz. This failure lasts for 58 +/- 20 seconds. There is a close correlation between the seizure and failure phenotypes; if a seizure occurs, a failure also occurs in greater than 95% of cases, while failures without seizures occurred in approximately 10% of cases. GF evoked responses by the DLM are abnormal during recovery from the buzz. After recovery, there is a refactory period during which a buzz is less effective at inducing seizures and failures.

Temporary paralysis following mechanical shock; sensitive only to initial shock, refractory thereafter. The bang-sensitive phenotype is suppressed by mle^nap-ts1 at its permissive temperature; the electrophysiology of the larval neuromuscular junction appears normal.