FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mst6
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General Information
Symbol
Dmel\mst6
Species
D. melanogaster
Name
FlyBase ID
FBal0006340
Feature type
allele
Associated gene
Dmel\mst
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Miklos et al., 1997)
Mutagen
ethyl methanesulfonate
(Perrimon et al., 1989)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Germ cells are unable to survive in germ line clones. Homozygous embryos do not exhibit any central or peripheral nervous system defects. Larvae have very little imaginal disc tissue and significantly reduced neural tissue. More than 60% of the cells have aneuploid or polyploid chromosome complements. Cytokinesis is normal.

      (Miklos et al., 1997)

      Lethality occurs during larval or pupal stages. Homozygous germline clones display cell lethality. Embryos derived from heterozygous mothers do not have CNS or PNS defects.

      (Perrimon et al., 1989)

      larval/pupal lethal

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Lefevre.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      LB20DA618
      (Miklos et al., 1997)
      l(1)19Fg6
      l(1)19FgDA618
      (Perrimon et al., 1989)
      l(1)DA618
      (Miklos et al., 1986)
      mst6
      Name Synonyms
      Secondary FlyBase IDs
        References (3)