FB2026_02 , released June 18, 2026
Allele: Dmel\Acly01466
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General Information
Symbol
Dmel\Acly01466
Species
D. melanogaster
Name
FlyBase ID
FBal0007976
Feature type
allele
Associated gene
Dmel\Acly
Associated Insertion(s)
P{PZ}Acly01466
Carried in Construct
Also Known As
ATPCL01466
Key Links
Genomic Maps

Allele class

hypomorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - molecular evidence

(Morciano et al., 2019)
Mutagen
P-element activity
Progenitor genotype
Associated Insertion(s)
P{PZ}Acly01466
Cytology
Description

Insertion within the 5'UTR, 340bp upstream of the ATPCL translation initiation site.

(Morciano et al., 2019)

P{PZ} insertion in intron 1 of the CT18257 transcript of ATPCL, 937bp downstream of the 5' end of the transcript.

(Misra, 2000.8.25)
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      ATPCL01466/Df(2R)Exel7138 larval neuroblasts show a small but significant increase in the frequency of chromosome breaks, which are not increased upon 2Gy irradiation; such chromosome breaks are almost absent in wild-type controls

      (Morciano et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      whd1/+ ATPCL01466/+ exhibit a decline in the cortical zone of lymph gland primary lobe of larvae when compared to controls.

      (Tiwari et al., 2020)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      A. Spradling.

      Comments
      Comments

      Complements: l(2)0507005070. Complements: spin08639a. Complements: l(2)k03501k03501. Complements: l(2)k05419ak05419a. Complements: spink06110. Complements: l(2)k09217k09217. Complements: l(2)k15617k15617.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      ATPCL-
      (Miao et al., 2022)
      ATPCL01466
      (Tiwari et al., 2020, Morciano et al., 2019)
      Acly01466
      l(2)01466
      (Misra, 2000.8.25, Spradling et al., 1999)
      l(2)0146601466
      (BDGP Project Members, 1994-1999)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)