FlyBase Allele Report: Dmel\rig[05056]

General Information

Symbol

Dmel\rig⁰⁵⁰⁵⁶

Species

D. melanogaster

Name

FlyBase ID

FBal0008075

Feature type

allele

Associated gene

Dmel\rig

Associated Insertion(s)

P{PZ}rig⁰⁵⁰⁵⁶

Carried in Construct

Also Known As

l(2)05056

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

Progenitor genotype

Associated Insertion(s)

P{PZ}rig⁰⁵⁰⁵⁶

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{PZ}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal

(Gates et al., 2004)

lethal (with Df(2R)exu1)

(Borg et al., 2015)

lethal (with Df(2R)exu2)

(Borg et al., 2015)

lethal (with rig^C063)

(Borg et al., 2015)

lethal (with rig^k07917)

(Borg et al., 2015)

lethal | recessive

(Borg et al., 2015, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of rig^{Scer\UAS.T:Avic\GFP-ECFP} driven by Scer\GAL4^da.PU induces supernumerary bodies that are largely nuclear in larval muscles; these foci are reduced and mostly restricted to cytoplasm in a rig⁰⁵⁰⁵⁶/rig^k07917 background.

(Borg et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

rig[+]/rig⁰⁵⁰⁵⁶ is a non-enhancer of visible phenotype of Hsap\MAPT^GMR.Ex.PJ

(Ambegaokar and Jackson, 2011)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

rig[+]/rig⁰⁵⁰⁵⁶ is a non-enhancer of eye phenotype of Hsap\MAPT^GMR.Ex.PJ

(Ambegaokar and Jackson, 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

One copy of rig⁰⁵⁰⁵⁶ under the control of Scer\GAL4^GMR.PS does not enhance the rough eye phenotype seen in flies expressing Hsap\MAPT^GMR.Ex.PJ.

(Ambegaokar and Jackson, 2011)

Complementation and Rescue Data

Fails to complement

rig^k07839

(Gates et al., 2004)

rig^k07917

(Gates et al., 2004)

Partially rescued by

rig⁰⁵⁰⁵⁶ is partially rescued by rig^UAS.ECFP/Scer\GAL4^da.PU

(Borg et al., 2015)

rig⁰⁵⁰⁵⁶/rig^k07917 is partially rescued by rig^UAS.ECFP/Scer\GAL4^da.PU

(Borg et al., 2015)

rig^C063/rig⁰⁵⁰⁵⁶ is partially rescued by rig^UAS.ECFP/Scer\GAL4^da.PU

(Borg et al., 2015)

Comments

Expression of rig^{Scer\UAS.T:Avic\GFP-ECFP} driven by Scer\GAL4^da.PU partially rescues lethality in rig^C063/rig⁰⁵⁰⁵⁶ (50% viable adults), rig^k07917/rig⁰⁵⁰⁵⁶ (55%) or rig⁰⁵⁰⁵⁶/rig⁰⁵⁰⁵⁶ (10%) mutants.

(Borg et al., 2015)

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

11391

cn¹ P{PZ}rig⁰⁵⁰⁵⁶/CyO; ry⁵⁰⁶ e¹

Notes on Origin

Discoverer

A. Spradling.

Separable from: a second-site female sterile mutation on the second chromosome.

(Gates et al., 2004)

Comments

"l(2)05056" was originally reported as an allele of bl, but "l(2)05056" complements bl^k08305. In addition, "l(2)k07917" and "l(2)k07839" fail to complement "l(2)05056" and complement bl^k08305. "l(2)05056", "l(2)k07917" and "l(2)k07839" therefore constitute a lethal complementation group that is distinct from bl and this complementation group is referred to as "rig". Complements: bl^k08305.

(Gates et al., 2004)

Complements: bl^k08305. Complements: l(2)00629⁰⁰⁶²⁹. Complements: l(2)05510⁰⁵⁵¹⁰. Complements: l(2)k02206^k02206. Complements: l(2)k07713^k07713. Complements: l(2)k16204^k16204. Complements: l(2)s4831^s4831.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Gem5^W

(Borg et al., 2015)

l(2)05056

(Gates et al., 2004, Spradling et al., 1999)

l(2)05056⁰⁵⁰⁵⁶

(BDGP Project Members, 1994-1999)

rig⁰⁵⁰⁵⁶

(Ambegaokar and Jackson, 2011)

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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