FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Rpt105643
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General Information
Symbol
Dmel\Rpt105643
Species
D. melanogaster
Name
FlyBase ID
FBal0008094
Feature type
allele
Associated gene
Dmel\Rpt1
Associated Insertion(s)
P{PZ}Rpt105643
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Salz, 2001.7.18, Misra, 2000.11.18, Salz, 2000.11.28, Spradling et al., 1999, FlyBase, 1996-, BDGP Project Members, 1994-1999)
Progenitor genotype
Associated Insertion(s)
P{PZ}Rpt105643
Cytology
Description

Insertion between nucleotides 31 an 32 of the Rpt1 5'UTR.

(Szabó et al., 2007)

P{PZ} insertion in exon 1 of the CT3016 transcript of Rpt1, 8bp downstream of the 5' end of the transcript. P{PZ} element is inserted in the same orientation as the gene.

(Misra, 2000.11.18)

The P{PZ}Rpt105643 insertion maps within both Rpt1 and CG17985 (nested genes).

(FlyBase, 1996-)
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  Huntington's disease
      modeled by Hsap\HTT128Q.1-336.UAS
      (Kaltenbach et al., 2007)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Rpt105643 is a suppressor of visible phenotype of Hsap\HTT128Q.1-336.UAS, Scer\GAL4GMR.PU

      (Kaltenbach et al., 2007)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Rpt105643 is a suppressor of eye phenotype of Hsap\HTT128Q.1-336.UAS, Scer\GAL4GMR.PU

      (Kaltenbach et al., 2007)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      A. Spradling.

      The P{PZ}Rpt105643 insertion is within Rpt1, which is located within a long intron of CG17985, thus the insertion may affect the expression of both genes. Homozygosity for the P{PZ}Rpt105643 chromosome results in second instar larval lethality.

      (Szabó et al., 2007)
      Comments
      Comments

      Complements: Cyt-b501857. Complements: scra03427. Complements: l(2)0849208492. Complements: l(2)k00107k00107. Complements: hrgk07619. Complements: scrak09008a. Complements: l(2)08492k10320.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      05643
      (Kaltenbach et al., 2007)
      Rpt105643
      (Szabó et al., 2007)
      l(2)05643
      (Misra, 2000.11.18, Salz, 2000.11.28, Spradling et al., 1999)
      l(2)0564305643
      (BDGP Project Members, 1994-1999)
      l(2)43Ed05643
      (Nagengast and Salz, 2001)
      Name Synonyms
      Secondary FlyBase IDs
        References (11)