FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Ankrd494
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General Information
Symbol
Dmel\Ankrd494
Species
D. melanogaster
Name
FlyBase ID
FBal0008489
Feature type
allele
Associated gene
Dmel\Ankrd49
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Ashburner et al., 1999.10.12, Woodruff and Ashburner, 1979)
Progenitor genotype
Cytology
Description

Amino acid replacement: H87Y.

(Strutt and Strutt, 2020)

Amino acid replacement: A156T.

(Strutt and Strutt, 2020)

Unspecified point mutation in l(2)35Be.

(Huen and Roote, 2010.5.4)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:15,006,827..15,006,827 [-]
Nucleotide change:

G15006827A

Amino acid change:

A156T | Ankrd49-PA

Reported amino acid change:

A156T

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase curator based on reported amino acid change.

(Strutt and Strutt, 2020)
point_mutation
2L:15,007,034..15,007,034 [-]
Nucleotide change:

C15007034T

Amino acid change:

H87Y | Ankrd49-PA

Reported amino acid change:

H87Y

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase curator based on reported amino acid change.

(Strutt and Strutt, 2020)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Pupal wings carrying clones of Ankrd494 exhibit delayed trichome initiation and formation of trichomes in the cell centre rather than at the distal cell edge when compared to controls.

      (Strutt and Strutt, 2020)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Ankrd494 is a suppressor | partially of wing hair phenotype of Scer\GAL4en-e16E, dcoUAS.cSa

      (Strutt and Strutt, 2020)

      Ankrd494 is a suppressor | partially of wing phenotype of Scer\GAL4en-e16E, dcoUAS.cSa

      (Strutt and Strutt, 2020)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Ankrd494 is rescued by Ankrd49Act5C.EGFP

      (Strutt and Strutt, 2020)
      Comments

      complements l(2)35Be3

      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Ashburner.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      Ankrd494
      DAnkrd49l(2)35Be4
      (Strutt and Strutt, 2020)
      SF5
      l(2)35Be4
      (Strutt and Strutt, 2020, Huen and Roote, 2010.5.4)
      l(2)br10SF5
      (Woodruff and Ashburner, 1979)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)