FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Mo2500274
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General Information
Symbol
Dmel\Mo2500274
Species
D. melanogaster
Name
FlyBase ID
FBal0009372
Feature type
allele
Associated gene
Dmel\Mo25
Associated Insertion(s)
P{PZ}Mo2500274
Carried in Construct
Also Known As
l(3)00274
Key Links
Genomic Maps

Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(He et al., 2005)
Mutagen
P-element activity
Progenitor genotype
Associated Insertion(s)
P{PZ}Mo2500274
Cytology
Description

Insertion into the 5' untranslated region.

(He et al., 2005)
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes and hemizygotes die as larvae without any morphological defect.

      Homozygous clones in the wing result in thickened wing veins and loss of the wing margin. Clones located some distance from a normal vein do not show any mutant phenotype and differentiate normal looking wing hairs. Homozygous clones often result in a multiple bristle phenotype (for example in the notum).

      (He et al., 2005)

      Homozygotes die during the first to third larval instar stages. Embryos derived from homozygous female germ line clones show poor cuticle development. This phenotype can be partially paternally rescued.

      (Russell et al., 1998)

      Germline clones produce eggs with poor cuticle development.

      (Perrimon et al., 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Mo25[+]/Mo2500274 is an enhancer of visible phenotype of Nno1

      (He et al., 2005)

      Mo25[+]/Mo2500274 is an enhancer of visible phenotype of Delta05151

      (He et al., 2005)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Mo25[+]/Mo2500274 is an enhancer of wing margin phenotype of Nno1

      (He et al., 2005)

      Mo25[+]/Mo2500274 is an enhancer of wing vein phenotype of Delta05151

      (He et al., 2005)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The weak wing notching phenotype seen in Nno1 flies is enhanced by Mo2500274/+.

      The expanded wing vein phenotype seen in Dl05151/+ flies is enhanced by Mo2500274/+.

      (He et al., 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      A. Spradling.

      Comments
      Comments

      Complements: Baldspot01895. Complements: Baldspot02281. Complements: l(3)73Ah02540. Complements: Baldspot03229. Complements: Baldspot03234. Complements: Baldspot04106. Complements: Abl04674. Complements: argos05845. Complements: argos05959. Complements: Baldspot06519. Complements: l(3)neo201. Complements: Baldspotneo21. Complements: Baldspotneo22.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      Dmo2500274
      (He et al., 2005)
      Dmo25P
      (He et al., 2005)
      Mo2500274
      l(3)00274
      (Spradling et al., 1999, Russell et al., 1998)
      l(3)0027400274
      (Perrimon et al., 1996, Meister and Braun, 1995.10, BDGP Project Members, 1994-1999)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)