FlyBase Allele Report: Dmel\Ssdp[neo48]

General Information

Symbol

Dmel\Ssdp^neo48

Species

D. melanogaster

Name

FlyBase ID

FBal0011061

Feature type

allele

Associated gene

Dmel\Ssdp

Associated Insertion(s)

P{hsneo}Ssdp^neo48

Carried in Construct

Also Known As

l(3)neo48¹

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Cooley et al., 1988)

Progenitor genotype

Associated Insertion(s)

P{hsneo}Ssdp^neo48

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:18,196,866..18,196,866 [+]

(de Navascués and Modolell, 2010, Spradling et al., 1999, Cooley et al., 1988)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | germline clone | larval stage | recessive

(Chen et al., 2002)

lethal | recessive

(Chen et al., 2002, Spradling et al., 1999, Cooley et al., 1988)

partially lethal (with Ssdp^EP3097)

(van Meyel et al., 2003)

visible | somatic clone

(de Navascués and Modolell, 2007)

Phenotype Manifest In

adult cuticle | somatic clone

(de Navascués and Modolell, 2007)

macrochaeta (with Ssdp^EP3097)

(van Meyel et al., 2003)

mesonotum (with Ssdp^EP3097)

(van Meyel et al., 2003)

wing (with Ssdp^EP3097)

(van Meyel et al., 2003)

wing | cell non-autonomous | dorsal | somatic clone

(van Meyel et al., 2003)

wing | dorsal | somatic clone

(van Meyel et al., 2003)

wing | somatic clone

(van Meyel et al., 2003)

wing margin bristle | cell non-autonomous | dorsal | ectopic | somatic clone

(van Meyel et al., 2003)

Detailed Description

Statement

Reference

Homozygous clones result in cuticle defects in the adult.

(de Navascués and Modolell, 2007)

35% of Ssdp^EP3097/Ssdp^neo48 individuals survive through eclosion. Most of these flies display mutant phenotypes including wing blisters, a mild cleft in the notum along the anterior posterior axis, and thin gnarled macrochaetae on the notum. When Ssdp^neo48 clones are induced in the wing, a range of phenotypes are seen. Ectopic margin formation with or without by ectopic outgrowth. The Outgrowths are associated with mutant cells but not entirely made up of them. Phenotypes are never associated with ventral clones. When clones straddle the margin on both dorsal and ventral surfaces wing nicking is seen.

(van Meyel et al., 2003)

Animals lacking both maternal and zygotic Ssdp die at the beginning of the second larval instar.

(Chen et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhancer of

Statement

Reference

Ssdp^neo48 is an enhancer of wing phenotype of Bx^J

(Chen et al., 2002)

NOT Enhancer of

Statement

Reference

Ssdp^neo48 is a non-enhancer of phenotype of Chi^e5.5

(van Meyel et al., 2003)

NOT Suppressor of

Statement

Reference

Ssdp^neo48 is a non-suppressor of phenotype of Chi^e5.5

(van Meyel et al., 2003)

Other

Statement

Reference

Chi^e5.5, Ssdp^neo48 has wing phenotype

(Chen et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Double heterozygotes for Chi^e5.5 and Ssdp^neo48 have scalloped wings. The addition of Ssdp^neo48 enhances the wing scalloping phenotype seen in Bx^J animals. No wing scalloping is seen when combined with ap⁴ or ap^56f.

(Chen et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

Ssdp^L5

(van Meyel et al., 2003)

Ssdp^L7

(van Meyel et al., 2003)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Cooley et al.

(Cooley et al., 1988)

Comments

Complements: l(3)00643⁰⁰⁶⁴³. Complements: cpo⁰¹⁴³². Complements: sr⁰³⁹⁹⁹. Complements: l(3)05697⁰⁵⁶⁹⁷.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

Ssdp^l(3)neo48

(van Meyel et al., 2003)

Ssdp^neo48

(de Navascués and Modolell, 2010, de Navascués and Modolell, 2007)

l(3)neo48

(Spradling et al., 1999)

l(3)neo48¹

(Chen et al., 2002, BDGP Project Members, 1994-1999, Cooley et al., 1988)

ssdp^neo48

(Bronstein et al., 2010)

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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