FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\lzD
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General Information
Symbol
Dmel\lzD
Species
D. melanogaster
Name
Dominant
FlyBase ID
FBal0011819
Feature type
allele
Associated gene
Dmel\lz
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Males and homozygous females resemble lzs. Heterozygous females sometimes have roughened eyes. Apparent dominance shown by H. Bender to be caused by the presence of svspa-e(lz); heterozygous expression additionally enhanced by presence of In(2LR)bwV1. spectacle; tarsal structures reduced or absent; spermathecae absent; parovaria absent female-sterile

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      lzD is a suppressor of hemocyte phenotype of PPO1Bc

      (Rizki and Rizki, 1981)

      lzD is a suppressor of hemolymph phenotype of PPO1Bc

      (Rizki and Rizki, 1981)

      lzD is a suppressor of embryonic/larval lymph gland phenotype of PPO1Bc

      (Rizki and Rizki, 1981)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Causes suppression of paracrystalline inclusions in hemocytes of Bc1 larvae. Also suppresses heat-induced blackening of crystal cells in the Bc1 hemolymph and lymph glands.

      (Rizki and Rizki, 1981)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Novitski, Sep. 1947.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      lzD
      Name Synonyms
      Dominant
      Secondary FlyBase IDs
        References (5)