FlyBase Allele Report: Dmel\mw[1]

General Information

Symbol

Dmel\mw¹

Species

D. melanogaster

Name

FlyBase ID

FBal0012670

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Also Known As

Key Links

Allele class

Mutagen

spontaneous

Nature of the Allele

Allele class

Mutagen

spontaneous

(Muller, 1946)

Progenitor genotype

Cytology

Polytene chromosomes normal.

(Oster, 1957)

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Introduction of extra heterochromatin (an extra Y chromosome in the male) does not affect the action of mw¹.

(Oster, 1957)

Produces no visible phenotype in a wild-type background.

(Muller, 1946)

w alleles that are sensitive to mw¹ are insertion alleles; at least six different transposable are elements involved. Insensitive w alleles are not insertion mutants. RK1.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

mw¹ is an enhancer of abnormal eye color phenotype of w^h

(Birchler et al., 1989)

mw¹ is an enhancer of abnormal eye color phenotype of w^zm, z¹

(Birchler et al., 1989)

mw¹ is an enhancer of abnormal eye color phenotype of w^bf

(Birchler et al., 1989)

mw¹ is an enhancer of abnormal eye color phenotype of w^a4

(Birchler et al., 1989)

mw¹ is an enhancer of abnormal eye color phenotype of w^sp55

(Birchler et al., 1989)

mw¹ is an enhancer of abnormal eye color phenotype of w^a

(Gelbart, 1971, Muller, 1946)

Phenotype Manifest In

Enhancer of

Statement

Reference

mw¹ is an enhancer of pigment cell phenotype of w^h

(Birchler et al., 1989)

mw¹ is an enhancer of pigment cell phenotype of w^zm, z¹

(Birchler et al., 1989)

mw¹ is an enhancer of pigment cell phenotype of w^bf

(Birchler et al., 1989)

mw¹ is an enhancer of pigment cell phenotype of w^a4

(Birchler et al., 1989)

mw¹ is an enhancer of pigment cell phenotype of w^sp55

(Birchler et al., 1989)

mw¹ is an enhancer of pigment cell phenotype of w^a

(Gelbart, 1971, Muller, 1946)

Suppressor of

Statement

Reference

mw¹ is a suppressor of phenotype of w^sp55

Additional Comments

Genetic Interactions

Statement

Reference

Dilutes, in a variegated fashion, the phenotype of w^a and seven other intermediate w alleles.

(Gelbart, 1971)

A specific modifier of w^a and other intermediate alleles at the w locus; it makes the colour of the eyes much lighter, especially in the female. The eye colour is patchy in these flies and there is considerable variation between individuals as well as between the two eyes of the same fly, although there is a positive correlation between the latter. Classification is always possible.

(Muller, 1946)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

149

w^a mw¹ mit¹

Notes on Origin

Discoverer

Muller, 1946.

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

(Gelbart, 1971, Oster, 1957, Muller, 1946)

mw¹

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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