FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Nl1N-1
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General Information
Symbol
Dmel\Nl1N-1
Species
D. melanogaster
Name
FlyBase ID
FBal0012876
Feature type
allele
Associated gene
Dmel\N
Associated Insertion(s)
?{}Nl1N-1
Carried in Construct
Also Known As
l(1)N
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
Progenitor genotype
Associated Insertion(s)
?{}Nl1N-1
Cytology
Description

Insertion of a copia-like element at coordinate -24kb (coordinates according to FBrf0045027 and FBrf0039003).

(Kelley et al., 1987)

Nl1N-1 is associated with a 8.5 kb insertion between coordinates -24.2 and -23.0 about 2.3 kb to the right of the insertion associated with N55e11 (Kidd, Lockett and Young, 1983).

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Nl1N-1/+ females are wild type; Nl1N-1/N females and Nl1N-1/Y males are lethal; l(1)N/Y;Dp(1;2)51b males are Co-like. Heterozygotes with recessive visibles at Notch are wild type. Developmental defects in Nl1N-1/Y males are more limited than in N/Y males and the defects are confined to the anterior ectoderm (Poulson, 1967; Poulson, 1968). Like N mutants, Nl1N-1 mutants are defective as embryos (Shellenbarger and Mohler, 1975; Mohler, 1978).

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Welshons.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Nl1N-1
      l(1)N
      (Kelley et al., 1987, Shellenbarger and Mohler, 1975)
      l(1)N1
      lN
      Name Synonyms
      Secondary FlyBase IDs
        References (7)