FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\neb1
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General Information
Symbol
Dmel\neb1
Species
D. melanogaster
Name
FlyBase ID
FBal0012931
Feature type
allele
Associated gene
Dmel\neb
Associated Insertion(s)
P{ry11}neb1
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Molina et al., 1997)
Progenitor genotype
Associated Insertion(s)
P{ry11}neb1
Cytology
Description

Insertion within the intron.

(Molina et al., 1997)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mitotic chromosome segregation is abnormal, as shown by mitotic figures. The arrangement of chromosomes and centrosomes exhibits a variety of defects.

      (Molina et al., 1997)

      late lethal Some homozygotes survive until the pupal period, but very few eclose. Squash preparations of pupal testes reveal that the mitochondrial derivative (nebenkern) fails to elongate during spermatid differentiation. Flagellar axonemes are assembled. Onion stage early spermatids appear normal.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Berg, McKearin and Spradling

      Comments
      Comments

      Reversion analysis demonstrates the insertion is responsible for the mutant phenotype.

      (Molina et al., 1997)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      neb1
      sl(2)ry3
      tio1
      (Molina et al., 1997)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)