FB2026_02 , released June 18, 2026
Allele: Dmel\nonA2
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General Information
Symbol
Dmel\nonA2
Species
D. melanogaster
Name
FlyBase ID
FBal0013084
Feature type
allele
Associated gene
Dmel\nonA
Associated Insertion(s)
Carried in Construct
Also Known As
nonAP14
Key Links
Genomic Maps

Allele class

loss of function allele

hypomorphic allele - genetic evidence

Mutagen
    Nature of the Allele
    Allele class

    hypomorphic allele - genetic evidence

    (Stanewsky et al., 1993)

    loss of function allele

    (Rendahl and Hall, 1996)
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Nucleotide substitution: G4407A. Amino acid replacement: G400D. Mutation is within the second RRM repeat.

    (Rendahl et al., 1996)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    X:16,364,199..16,364,199 [+]
    Nucleotide change:

    G16364199A

    Reported nucleotide change:

    G4407A

    Amino acid change:

    G400D | nonA-PA; G400D | nonA-PB; G400D | nonA-PC; G400D | nonA-PD

    Reported amino acid change:

    G400D

    (Rendahl et al., 1996)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference

        The full-length nonA protein is produced in nonA2 adult males and females but at a substantially reduced level relative to wild type. No detectable differences in spatial location were observed between mutant and wild type proteins in adults.

        (Rendahl et al., 1992)
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Optomotor blind and wild-type courtship song.

        (Rendahl and Hall, 1993)

        nonA2/nonA9 males produce normal courtship songs. Males sing normally.

        (Kulkarni et al., 1988)

        does not complement nonA9 song defects

        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer

        Pak.

        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        nonA2
        nonAP14
        (Rendahl and Hall, 1996, Rendahl et al., 1996, Rendahl and Hall, 1993, Stanewsky et al., 1993, Rendahl et al., 1992, Kulkarni et al., 1988)
        Name Synonyms
        Secondary FlyBase IDs
          References (6)