FlyBase Allele Report: Dmel\qs[2]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\qs²

General Information

Symbol

Dmel\qs²

Species

D. melanogaster

Name

FlyBase ID

FBal0014146

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Lindsley and Zimm, 1992)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Pentz et al., 1990)

partially lethal - majority live | female | recessive

(Pentz et al., 1990)

viable | cold sensitive

(Pentz et al., 1990)

(Pentz et al., 1990)

Phenotype Manifest In

adult cuticle | male

(Pentz et al., 1990)

macrochaeta | male

(Pentz et al., 1990)

puparium cuticle

(Pentz et al., 1990)

Detailed Description

Statement

Reference

Mutation is leaky, some hemizygous males survive. Viability of these males is reduced at 18^oC. Male adult cuticle and bristles are very pale with a yellowish cast. Pupae cases are also very pale. Recovered as suppressor of b; cold-sensitive in males and females. At 25^oC, qs²/qs² females only 1% viable but qs²/Y males as viable as wild type.

(Pentz et al., 1990)

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

qs² is a suppressor of phenotype of Adc^74b4

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^71k2

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^83f51

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^83d36

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^79a4

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^81a2

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^77a3

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^79d2

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^74c4

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^84g

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^78g

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^79d10

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^76f3

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^74d6

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^77a1

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^84h34

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^74c5

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^83l

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^76j2

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^81c2

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^79d4

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^78k1

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^76e2

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^83d35

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^77j

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^76e1

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^78k5

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^79h2

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^76b1

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^74c2

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^83f17

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^82c3

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^79df2

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^79b7

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^81c17

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^77a4

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^77a2

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^79b1

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^79g2

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^79d11

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^82c7

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^83c20

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^75a

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^78f2

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^83f18

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^83c36

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc⁶⁶¹

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^83b40

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^78a

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^83c25

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^77a5

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^83f52

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^78k3

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^79h3

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^79d13

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^76k2

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^83d29b

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^83c47

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^74b5

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^78f1

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^81c

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^83c26

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^74b2

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^81k

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^81f3

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^83c35b

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^78k2

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^76k1

(Alexandrov and Alexandrova, 1986)

qs² is a suppressor of phenotype of Adc^79d8

(Alexandrov and Alexandrova, 1986)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

4348

107698

Notes on Origin

Discoverer

Sherald.

(Lindsley and Zimm, 1992)

Comments

Comments

Mutation decreases phenol oxidase activity. The thermolabile profile suggest that the thermostable component is absent or altered. At 60^oC both the qs² activators are inactivated within 2 minutes. A large build up of the DOPA pool suggests the function that produces DOPA may not be affected. The catecholamine pool size is reduced.

(Pentz et al., 1990)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

qs²

su(b)¹⁸

(The Moscow Regional Drosophila melanogaster Stock Center, Dubna, Alexandrov and Alexandrova, 1986)

su¹⁸

(Lindsley and Zimm, 1992)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections