ftd, faintoid, su(b)18
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\qs using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\qs in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
A screen for X-linked genes that affect embryo morphology revealed qs.
Recessive embryonic lethal; denticles and mouthparts unpigmented; cell viable in gynandromorphs causing depigmentation of cuticle, including chaetae; viability reduced owing to weakened cuticle. Used as marker in the analysis of mosaic embryos (Gergen and Wieschaus, 1985). qs1, qs2, and qs3 hypomorphic in that expression varies with temperature and nutrition; some survival when reared on enriched medium; survivors smaller than normal and incompletely pigmented with a yellowish tinge; some extremely pale with bristles with very little pigmentation and with wings that when expanded are glassy clear and very fragile. The extremely pale qs2/Y never exhibit melanotic wound reaction and puparia underpigmented. qs embryos derived from homozygous germ-line clones do not hatch and exhibit head defects and abnormalities of germ-band shortening; heterozygous embryos from such clones exhibit 75% survival; homozygous clones behave as meiotic mutant yielding 8% patroclinous males (Wieschaus and Noell, 1986). Phenol oxidase activity of any surviving qs flies significantly depressed, in some cases being undetectable; all three components, A1, A2 and A3, coordinately reduced; activator activity normal. Phenol oxidase deficiency leads to significant accumulations of catecholamine pools in qs2 males 60 to 80 min after eclosion: three-to-eight-fold increases in N-β-alanyldopamine and N-acetyldopamine and two-fold increases in dopamine (Pentz, Black and Wright, 1990).