FlyBase Allele Report: Dmel\r[sP1]

General Information

Symbol

Dmel\r^sP1

Species

D. melanogaster

Name

FlyBase ID

FBal0014357

Feature type

allele

Associated gene

Dmel\r

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

spontaneous

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Zerges et al., 1992)

Mutagen

spontaneous

Progenitor genotype

Cytology

Description

Point mutant or small insertion.

(Zerges et al., 1992)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die during embryonic stage | maternal effect | recessive

(Zerges et al., 1992)

some die during embryonic stage | recessive | maternal effect | recessive

(Zerges et al., 1992)

visible | recessive

(Hiebert and Birchler, 1994, Zerges et al., 1992)

Phenotype Manifest In

wing

(Hiebert and Birchler, 1994)

Detailed Description

Statement

Reference

Truncated wing phenotype. r^sP1 males that are also homozygous for mle⁴ show a less severe rudimentary phenotype than their mle⁴/+ sibs.

(Hiebert and Birchler, 1994)

Oblique wing truncation in homozygotes.

(Zerges et al., 1992)

RK2.

(Craymer, 1980)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

r^sP1 has phenotype, non-enhanceable by Low[+]/Low¹

(Bhadra et al., 1997)

Suppressed by

Statement

Reference

r^sP1 has wing phenotype, suppressible by su(Hw)²

(Zerges et al., 1992)

r^sP1 has wing phenotype, suppressible by su(Hw)⁷

(Zerges et al., 1992)

r^sP1 has wing phenotype, suppressible by su(Hw)⁸

(Zerges et al., 1992)

r^sP1 has phenotype, suppressible by su(Hw)²

(Craymer, 1980)

NOT suppressed by

Statement

Reference

r^sP1 has phenotype, non-suppressible by Low[+]/Low¹

(Bhadra et al., 1997)

Additional Comments

Genetic Interactions

Statement

Reference

The phenotype of hemizygous males is not affected by a single copy of Low¹.

(Bhadra et al., 1997)

Suppressed by mutations at su(Hw), where su(Hw) mutation behaves recessively. Temperature-dependent suppression reported by Craymer DIS 55:197 not observed.

(Zerges et al., 1992)

r phenotype can be partially suppressed by su(Hw)² at 25^oC and fully suppressed at 18^oC.

(Craymer, 1980)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Craymer, Nov. 1977.

(Craymer, 1980)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

r^sP1

r^sP

(Craymer, 1980)

r^sp1

(Bhadra et al., 1997, Hiebert and Birchler, 1994, Rabinow and Birchler, 1990)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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