FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\row
Open Close
General Information
Symbol
Dmel\row
Species
D. melanogaster
Name
FlyBase ID
FBal0014637
Feature type
allele
Associated gene
Dmel\ro
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
Progenitor genotype
Cytology
Description

nonsense mutation in homeobox

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Semi-lethal.

      (Knibb et al., 1993)

      row flies carrying one copy of roH3 have both wild-type and mutant ommatidia, the mutant ommatidia usually containing 8 but occasionally containing as many as 10 photoreceptor cells. The mutant ommatidia either have fewer or the normal number of outer photoreceptor cells, and the extra photoreceptors have features characteristic of the inner R7 and R8 photoreceptors.

      (Lockett et al., 1993)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      row has phenotype, suppressible by Dfd::rotLa

      (Lockett et al., 1993)

      row has ommatidium phenotype, suppressible by Dfd::roHTH

      (Lockett et al., 1993)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      row flies carrying one copy of Dfd::roHTH usually have 6 photoreceptors per ommatidium, in contrast to the 4-5 per ommatidium seen in row flies and 7 per ommatidium seen in wild-type flies. row flies carrying one copy of Dfd::rotLa show a slight increase in the number of outer photoreceptor cells compared to row flies. Rescue of the row phenotype increases as the number of copies of Dfd::rotLa is increased, with row flies carrying 4 copies of Dfd::rotLa having an average of 6 photoreceptor cells per ommatidium. Phenotype is completely rescued by two copies Dfd::roHTH.

      (Lockett et al., 1993)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      row is rescued by ro+t6.8

      (Lockett et al., 1993)
      Partially rescued by

      row is partially rescued by roH3

      (Lockett et al., 1993)
      Comments

      Phenotype is completely rescued by one copy of ro+t6.8 and two copies of roH3.

      (Lockett et al., 1993)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      roW
      (Knibb et al., 1993)
      row
      Name Synonyms
      Secondary FlyBase IDs
        References (3)