FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\roH3
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General Information
Symbol
Dmel\roH3
Species
D. melanogaster
Name
FlyBase ID
FBal0056234
Feature type
allele
Associated gene
Dmel\ro
Associated Insertion(s)
Carried in Construct
P{ro[H3Dfd]}
Key Links
Transgenic product class
missense_variant
(Lockett et al., 1993)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Lockett et al., 1993)
Mutagen
in vitro construct
(Lockett et al., 1993)
Progenitor genotype
Carried in construct
P{ro[H3Dfd]}
Cytology
Description

Construct: Arg43 in helix 3 of the homeodomain has been changed to a Thr (the amino acid residue found in the corresponding position in the Dfd gene).

(Lockett et al., 1993)
Allele components
Component
Use(s)
Encoded product / tool
ro
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      row flies carrying one copy of roH3 have both wild-type and mutant ommatidia, the mutant ommatidia usually containing 8 but occasionally containing as many as 10 photoreceptor cells. The mutant ommatidia either have fewer or the normal number of outer photoreceptor cells, and the extra photoreceptors have features characteristic of the inner R7 and R8 photoreceptors.

      (Lockett et al., 1993)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      roH3 partially rescues row

      (Lockett et al., 1993)
      Comments

      A single copy of roH3 almost completely rescues the row phenotype, while two copies of roH3 completely rescue the row phenotype.

      (Lockett et al., 1993)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      roH3
      Name Synonyms
      Secondary FlyBase IDs
        References (1)