FB2026_02 , released June 18, 2026
Allele: Dmel\Adcy13
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General Information
Symbol
Dmel\Adcy13
Species
D. melanogaster
Name
FlyBase ID
FBal0014880
Feature type
allele
Associated gene
Dmel\Adcy1
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Feany, 1990)
Mutagen
ethyl methanesulfonate
(Lindsley and Zimm, 1992, Feany, 1990)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Reduction in basal level of adult adenylate cyclase. Calcium sensitive. Transheterozygote females dncM14/rut2 and dncM14/rut3 deposit eggs that lack germ cells and display discrete morphological defects.

      (Whitehouse-Hills et al., 1992)

      Flies learn as well as wild-type controls. Hemizygous flies show essentially wild-type activation and inhibition of adenylate cyclase at various concentrations of calcium ions, although the basal level of adenylate cyclase activity is reduced.

      (Feany, 1990)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Gregory.

      (Lindsley and Zimm, 1992)

      Selected as: Suppressor of the sterility caused by dncM14.

      (Feany, 1990)

      Recovered as partial suppressor of the female sterility of homozygous dnc females.

      (Lindsley and Zimm, 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Adcy13
      BG3
      (Lindsley and Zimm, 1992)
      rut3
      Name Synonyms
      Secondary FlyBase IDs
        References (4)