FB2026_02 , released June 18, 2026
Allele: Dmel\scd1
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General Information
Symbol
Dmel\scd1
Species
D. melanogaster
Name
FlyBase ID
FBal0015262
Feature type
allele
Associated gene
scd
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      prothoracic tarsal segment 2 & sex comb

      (Boube et al., 1997)

      sex comb | ectopic

      (Boube et al., 1997)
      Detailed Description
      Statement
      Reference

      Approximately 70% of scd1/Y males have a small distal sex comb (containing two teeth on average) on the second tarsal segment of the prothoracic leg.

      (Boube et al., 1997)

      Exhibits 1-2 sex comb teeth on the second tarsal segment of the prothoracic leg in hemizygous males. Homozygous females viable and fertile. Interacts with Sco in that scd;Sco/+ males have reduced viability and lack many bristles, including many of the sex comb teeth on the first tarsal segment of the prothoracic leg. Resembles description of rare Sco homozygotes.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      scd1 has prothoracic tarsal segment 2 phenotype, enhanceable by Dp(3;Y)Antp+

      (Boube et al., 1997)

      scd1 has sex comb phenotype, enhanceable by Dp(3;Y)Antp+

      (Boube et al., 1997)

      scd1 has sex comb phenotype, enhanceable by Dp(3;3)M86D+2

      (Boube et al., 1997)

      scd1 has prothoracic tarsal segment 2 phenotype, enhanceable by Dp(3;3)M86D+2

      (Boube et al., 1997)

      scd1 has prothoracic tarsal segment 2 phenotype, enhanceable by RasGAP1sxt-BJ61

      (Boube et al., 1997)

      scd1 has sex comb phenotype, enhanceable by RasGAP1sxt-BJ61

      (Boube et al., 1997)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The sex comb phenotype of scd1/Y males is enhanced by Dp(3;Y)Antp+; the penetrance of the phenotype is increased to 100%, and the number of ectopic sex comb teeth is increased to approximately four. A similar enhancement of the phenotype is also caused by Dp(3;3)M86D+2 or Gap1sxt-BJ61. scd1/Y Scr4/+ males lack the small distal sex comb, but the sex comb on the first tarsal segment of the leg contains more teeth than the sex comb of Scr4/+ heterozygous males.

      (Boube et al., 1997)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      scd
      (Boube et al., 1997)
      scd1
      Name Synonyms
      Secondary FlyBase IDs
        References (1)