FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Scr17
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General Information
Symbol
Dmel\Scr17
Species
D. melanogaster
Name
FlyBase ID
FBal0015293
Feature type
allele
Associated gene
Dmel\Scr
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - genetic evidence

loss of function allele

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Sivanantharajah and Percival-Smith, 2009)

loss of function allele

(Long et al., 1996, Pattatucci et al., 1991)
Mutagen
X ray
(Pattatucci et al., 1991)
Progenitor genotype
Cytology

Polytene chromosomes normal.

(Pattatucci et al., 1991)
Description

Deletion of nucleotides 2,667,211-2,663,845 (numbering based on nucleotide position of chromosome arm 3R, according to genome release number 5.7). This 3.4kb deletion removes the 3' portion of the second exon, a splice site and a portion of the second intron. Scr17 has the potential to encode a truncated protein of 242 amino acid residues.

(Sivanantharajah and Percival-Smith, 2009)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3R:6,838,123..6,841,489 [-]
Comment:

Reported as a deletion of nucleotides 2,667,211-2,663,845, FlyBase R5.7.

(Sivanantharajah and Percival-Smith, 2009)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heterozygous males have a reduction in the number of sex comb bristles on the prothoracic leg compared to wild-type males.

      (Sivanantharajah and Percival-Smith, 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Enhancer of
      Statement
      Reference

      Scr[+]/Scr17 is a non-enhancer of wing vein | ectopic phenotype of Snr1E1

      (Marenda et al., 2004)
      NOT Suppressor of
      Statement
      Reference

      Scr[+]/Scr17 is a non-suppressor of wing vein | ectopic phenotype of Snr1E1

      (Marenda et al., 2004)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Pultz.

      (Lindsley and Zimm, 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Scr17
      (Becker et al., 2016, Estacio-Gómez et al., 2013, Roper, 2012, Sivanantharajah and Percival-Smith, 2009)
      Scrp18
      (Pattatucci et al., 1991)
      Name Synonyms
      Secondary FlyBase IDs
        References (8)