FlyBase Allele Report: Dmel\skd[1]

General Information

Symbol

Dmel\skd¹

Species

D. melanogaster

Name

FlyBase ID

FBal0015675

Feature type

allele

Associated gene

Dmel\skd

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Gindhart and Kaufman, 1995)

Mutagen

ethyl methanesulfonate

(Kennison and Tamkun, 1988)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Kennison and Tamkun, 1988)

Phenotype Manifest In

Detailed Description

Statement

Reference

Mutation does not affect the level of w expression in ph-p^lac+3 flies.

(Fauvarque et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

skd¹ is a non-enhancer of visible phenotype of Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA}

(Armstrong et al., 2005)

NOT Suppressor of

Statement

Reference

skd¹ is a non-suppressor of visible phenotype of Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA}

(Armstrong et al., 2005)

skd¹ is a non-suppressor of lethal phenotype of Ras85D^V12.sev, sev^S11.Tag:MYC

(Maixner et al., 1998)

Phenotype Manifest In

Enhancer of

Statement

Reference

skd¹/skd[+] is an enhancer of wing vein | ectopic phenotype of Hcf^HR1

(Rodriguez-Jato et al., 2011)

NOT Enhancer of

Statement

Reference

skd¹ is a non-enhancer of eye phenotype of Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA}

(Armstrong et al., 2005)

Suppressor of

Statement

Reference

skd¹ is a suppressor of phenotype of Pc⁴

(Kennison and Tamkun, 1988)

NOT Suppressor of

Statement

Reference

skd¹ is a non-suppressor of eye phenotype of Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA}

(Armstrong et al., 2005)

Other

Statement

Reference

Hcf^HR1, skd¹/skd[+] has scutellar bristle | ectopic phenotype

(Rodriguez-Jato et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

30% of skd¹/+ ; Hcf^HR1 males have defects in rotation of the genitalia. 30% of skd¹/+ ; Hcf^HR1 flies have extra scutellar bristles. The expressivity of the ectopic wing vein phenotype seen in Hcf^HR1 mutants is increased by skd¹/+.

(Rodriguez-Jato et al., 2011)

The lethality caused by sev^{S11.T:Hsap\MYC} in combination with Ras85D^V12.sev is not suppressed by skd¹.

(Maixner et al., 1998)

Suppresses the extra sex comb phenotype of Pc⁴, Ts(YLt;2Lt)L124. Causes between 50% and 100% suppression of the Pc⁴/+ extra sex combs phenotype.

(Kennison and Tamkun, 1988)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

skd¹

(Mariappa et al., 2018, Rodriguez-Jato et al., 2011, Chang et al., 2007)

Name Synonyms

Secondary FlyBase IDs

References (12)

Report Sections

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