FB2026_02 , released June 18, 2026
Allele: Dmel\Su(crc)1
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General Information
Symbol
Dmel\Su(crc)1
Species
D. melanogaster
Name
FlyBase ID
FBal0016255
Feature type
allele
Associated gene
Su(crc)
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Lindsley and Zimm, 1992, Sparrow, 1981)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      A dominant suppressor of crc lethality. Expression is temperature-sensitive in Su(crc) crc/crc heterozygotes and Su(crc) crc hemizygotes with a temperature-sensitive period beginning before pupariation and ending at the time of pupation. The effective lethal period for the suppressor genotypes at 30oC is at the end of the pupal period, not during prepupal stages as is the case for crc homozygotes.

      (Lindsley and Zimm, 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Su(crc)1 is a suppressor of phenotype of crc1

      (Sparrow, 1981)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Dominant suppressor of crc1 lethality. This phenotype is temperature-sensitive; Su(crc)1 crc1 double homozygotes and Su(crc)1 crc1/crc1 flies do not survive at 30oC. The temperature-sensitive period begins before pupariation and ends about 12 hours post-pupariation. The effective lethal phase is at the end of the pupal period.

      (Sparrow, 1981)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Induced on: crc cn.

      (Lindsley and Zimm, 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Su(crc)1
      Su1
      (Sparrow, 1981)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)