FB2026_02 , released June 18, 2026
Allele: Dmel\tor3
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General Information
Symbol
Dmel\tor3
Species
D. melanogaster
Name
FlyBase ID
FBal0016911
Feature type
allele
Associated gene
Dmel\tor
Associated Insertion(s)
Carried in Construct
Also Known As
torHM
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Schupbach and Wieschaus, 1989, Tearle and Nusslein-Volhard, 1987)
Progenitor genotype
Cytology
Description

Amino acid replacement: I11N.

(Furriols et al., 1996)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:7,708,914..7,708,914 [-]
Nucleotide change:

T7708914A

Amino acid change:

I11N | tor-PA; I11N | tor-PD

(Furriols et al., 1996)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      91.3% of embryos derived from homozygous females terminate in the A7 abdominal segment.

      (Casci et al., 1999)

      The tor3 mutant phenotype is dosage sensitive, and is also sensitive to the dosage of the trk gene.

      (Furriols et al., 1996)

      Eggs derived from homozygous females cellularise normally but become abnormal at gastrulation; the cephalic furrow is shifted forward, the posterior midgut is missing and the germband forms to the posterior end of the embryo. The embryos lack anterior head structures and structures posterior to segment A7 (the labral segment and telson).

      (Schupbach and Wieschaus, 1989)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      tor3 has embryonic abdominal segment 8 phenotype, suppressible by styS73

      (Casci et al., 1999)

      tor3 has embryo | posterior phenotype, suppressible by styS73

      (Casci et al., 1999)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      If tor3 females are also heterozygous for styS73, 75% of the embryos terminate in the A7 abdominal segment, 25% terminate in the A8 abdominal segment and 17% are wild type.

      (Casci et al., 1999)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Schupbach, Wieschaus.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      tor3
      torHM
      (Casci et al., 1999, Furriols et al., 1996, Tearle and Nusslein-Volhard, 1987)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)