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General Information
Symbol
Dmel\styS73
Species
D. melanogaster
Name
FlyBase ID
FBal0096672
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

styS73/+ flies show a mild extra wing vein phenotype in 6.4% of adult flies grown at 29[o]C.

Homozygous clones in the adult abdomen do not show any consistent alterations of normal polarity.

Homozygous embryos have a tracheal phenotype. Homozygous clones in the eye result in ommatidia with an average of 10.6 photoreceptors per ommatidium. Most of the extra photoreceptors have small rhabdomeres and are positioned centrally, characteristic of the R7 or R8 class, although some of the extra photoreceptors are of the R1-R6 class. Most ommatidia in homozygous pupae have extra cone cells and extra primary pigment cells. styS73/styS88 animals occasionally survive to adulthood. These survivors have an excess of photoreceptor cells in the ommatidia. Transformation of some of the mystery cells to photoreceptors is seen in third larval instar eye imaginal discs. No excess R8 cells are seen (by staining with an anti-boss antibody) indicating that the extra photoreceptor cells are of the R7 type. styS73/styS88 adult survivors have extra wing vein material. Homozygous eggs are not recovered from females containing homozygous germ line clones, suggesting a requirement for sty function in the germline.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

styS73 has visible | dominant phenotype, enhanceable by aos[+]/aosΔ7

styS73 has visible | dominant phenotype, enhanceable by rho-5[+]/rho-5KO1

rho-5[+]/rho-5KO1, styS73 has visible | dominant phenotype, enhanceable by aos[+]/aosΔ7

aos[+]/aosΔ7, styS73 has visible | dominant phenotype, enhanceable by rho-5[+]/rho-5KO1

Enhancer of
Statement
Reference

sty[+]/styS73 is an enhancer of visible phenotype of spis.sev

sty[+]/styS73 is an enhancer of visible phenotype of rhohs.sev

sty[+]/styS73 is an enhancer of visible phenotype of Shs.sev

sty[+]/styS73 is an enhancer of visible phenotype of Egfr::tort4021E.hs.sev

Suppressor of
Statement
Reference

sty[+]/styS73 is a suppressor of visible | recessive phenotype of spiSCP1

sty[+]/styS73 is a suppressor of visible phenotype of aosGMR.PC

sty[+]/styS73 is a suppressor of visible phenotype of Egfrt1/Egfrf11

Other
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference

styS73 has wing vein phenotype, enhanceable by aos[+]/aosΔ7

styS73 has wing vein phenotype, enhanceable by rho-5[+]/rho-5KO1

rho-5[+]/rho-5KO1, styS73 has wing vein phenotype, enhanceable by aos[+]/aosΔ7

aos[+]/aosΔ7, styS73 has wing vein phenotype, enhanceable by rho-5[+]/rho-5KO1

Enhancer of
Statement
Reference

sty[+]/styS73 is an enhancer of adult optic lobe | adult stage phenotype of vap2

sty[+]/styS73 is an enhancer of eye phenotype of spis.sev

sty[+]/styS73 is an enhancer of eye phenotype of EgfrII.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF

sty[+]/styS73 is an enhancer of eye phenotype of rhohs.sev

sty[+]/styS73 is an enhancer of eye phenotype of Shs.sev

sty[+]/styS73 is an enhancer of eye phenotype of Egfr::tort4021E.hs.sev

Suppressor of
Statement
Reference

styS73 is a suppressor of photoreceptor cell R7 phenotype of sev14

styS73 is a suppressor | partially of embryo | posterior phenotype of trk5

sty[+]/styS73 is a suppressor of eye phenotype of aosGMR.PC

sty[+]/styS73 is a suppressor of eye phenotype of spiSCP1

styS73 is a suppressor | partially of embryo | posterior phenotype of tor3

sty[+]/styS73 is a suppressor of wing vein L4 phenotype of Egfrt1/Egfrf11

sty[+]/styS73 is a suppressor of anterior crossvein phenotype of Egfrt1/Egfrf11

sty[+]/styS73 is a suppressor of eye phenotype of Egfrt1/Egfrf11

Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

One copy of aosΔ7 enhances the extra wing vein phenotype seen in styS73 heterozygotes at 29[o]C.

One copy of rho-5KO1 enhances the extra wing vein phenotype seen in styS73 heterozygotes at 29[o]C.

One copy of aosΔ7 enhances the extra vein phenotype seen in rho-5KO1 styS73 double heterozygotes at 29[o]C.

One copy of rho-5KO1 enhances the extra vein phenotype seen in aosΔ7 styS73 double heterozygotes at 29[o]C.

Dominantly suppresses the rough eye phenotype of flies expressing argosGMR.PC. Dominantly suppresses the rough eye phenotype of spiSCP1 homozygotes. Dominantly suppresses the rough eye and wing vein phenotypes of Egfrt1/Egfrf11 flies. Dominantly enhances the rough eye phenotype of flies expressing rhohs.sev. Weakly dominantly enhances the eye phenotype of flies expressing spis.sev or Shs.sev. Weakly dominantly enhances the eye phenotype of flies expressing EgfrII.Scer\UAS under the control of Scer\GAL4GMR.PF. styS73/argosΔ7 double heterozygotes have a mild rough eye phenotype. Homozygous sev14 ommatidia have no R7 photoreceptors. R7 cells do form in sev14; styS73 double mutant ommatidia. In mosaic ommatidia, the only cell that needs to be mutant for styS73 for an R7 cell to form is the R7 cell itself. 98% of embryos derived from homozygous trk5 females terminate in the A7 abdominal segment. If the females are also heterozygous for styS73, 53% of the embryos terminate in the A7 abdominal segment, 39% terminate in the A8 abdominal segment and 8% are wild type. 91.3% of embryos derived from homozygous tor3 females terminate in the A7 abdominal segment. If the females are also heterozygous for styS73, 75% of the embryos terminate in the A7 abdominal segment, 25% terminate in the A8 abdominal segment and 17% are wild type. The eye phenotype of flies expressing Egfr::tort4021E.hs.sev is dominantly enhanced by styS73.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to complement
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Selected as: a dominant suppressor of the rough eye phenotype of flies expressing argosGMR.PC.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (4)