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General Information
Symbol
Dmel\spiSCP1
Species
D. melanogaster
Name
FlyBase ID
FBal0056119
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{ry11} insertion within 5' flanking sequences.

Insertion components
P{ry11}spiSCP1
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Mutant adults show a siginifican under-recruitment of photoreceptors in the eye. Misrotation of ommatidia is not seen.

Homozygous ommatidia show a reduction in the number of photoreceptor neurons.

Homozygotes have a rough eye phenotype.

95% homozygotes are viable. Homozygotes exhibit a rough eye phenotype, ommatidia have variable and reduced numbers of rhabdomeres and defects in the retinal basement membrane (cells with rhabdomeres appear below the retina). Hemizygotes exhibit enhanced rough eye phenotype and reduced viability.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference

spiSCP1 has visible | recessive phenotype, suppressible by sty[+]/styS73

spiSCP1 has visible | recessive phenotype, suppressible by sty[+]/styS88

Enhancer of
Statement
Reference

spiSCP1/spi[+] is an enhancer of abnormal cell polarity phenotype of S05671

Phenotype Manifest In
Enhanced by
Statement
Reference
Suppressed by
Statement
Reference

spiSCP1 has eye phenotype, suppressible by sty[+]/styS73

spiSCP1 has eye phenotype, suppressible by sty[+]/styS88

Enhancer of
Statement
Reference

spiSCP1/spi[+] is an enhancer of ommatidium phenotype of S05671

spiSCP1/spi[+] is an enhancer of photoreceptor phenotype of S05671

Additional Comments
Genetic Interactions
Statement
Reference

The loss of photoreceptor neurons seen in spiSCP1/spiSCP1 animals is enhanced by edlJV/Df(2R)edl-L19.

Null alleles of ru interact dominantly with spiSCP1 and spiSCP2.

The spiSCP1 rough eye phenotype is dominantly suppressed by styS73 or styS88.

The rough eye phenotype is partially rescued by argos::spiAS.Scer\UAS expressed under the control of Scer\GAL4hs.2sev.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Rescued by
Comments

spis.sev can rescue the eye specific mutation.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (7)