Open Close
General Information
Symbol
Dmel\tor3
Species
D. melanogaster
Name
FlyBase ID
FBal0016911
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
torHM
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

T7708914A

Amino acid change:

I11N | tor-PA; I11N | tor-PD

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: I11N.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

91.3% of embryos derived from homozygous females terminate in the A7 abdominal segment.

The tor3 mutant phenotype is dosage sensitive, and is also sensitive to the dosage of the trk gene.

Eggs derived from homozygous females cellularise normally but become abnormal at gastrulation; the cephalic furrow is shifted forward, the posterior midgut is missing and the germband forms to the posterior end of the embryo. The embryos lack anterior head structures and structures posterior to segment A7 (the labral segment and telson).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Statement
Reference

tor3 has embryo | posterior phenotype, suppressible | partially by styS73

Additional Comments
Genetic Interactions
Statement
Reference

If tor3 females are also heterozygous for styS73, 75% of the embryos terminate in the A7 abdominal segment, 25% terminate in the A8 abdominal segment and 17% are wild type.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Schupbach, Wieschaus.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (4)