FB2026_02 , released June 18, 2026
Allele: Dmel\tra5
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General Information
Symbol
Dmel\tra5
Species
D. melanogaster
Name
FlyBase ID
FBal0017008
Feature type
allele
Associated gene
Dmel\tra
Associated Insertion(s)
Carried in Construct
Also Known As
trav2
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Yuan and Belote, 1995, Taylor et al., 1994, Belote et al., 1990)
Mutagen
ethyl methanesulfonate
(Yuan and Belote, 1995, Belote et al., 1989, McKeown et al., 1987)
Progenitor genotype
Cytology

not detectably rearranged.

Polytene chromosomes normal.

(McKeown et al., 1987)
Description

Amino acid replacement: Q62term.

(Yuan and Belote, 1995)

Nucleotide substitution: C?T.

(Yuan and Belote, 1995)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3L:16,590,612..16,590,612 [-]
Nucleotide change:

C16590612T

Amino acid change:

Q62term | tra-PA

Comment:

Position of mutation on reference sequence inferred by FlyBase curator based on author statement: Produces a truncated protein of 61 amino acids.

(Yuan and Belote, 1995)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      100% of XX and XY tra5/Df(3L)st-j7 flies show male-specific courtship when paired with mature virgin females.

      (Taylor et al., 1994)

      Females exhibit segment spanning muscles in the fifth abdominal segment indicative of a transformation to the male specific phenotype. Somatic development of males is unaffected.

      (Taylor, 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Hoffmann.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      tra5
      traV2
      (Bhaskar et al., 2022)
      trav2
      (Evans and Cline, 2007, Yuan and Belote, 1995, Belote et al., 1989, McKeown et al., 1987)
      Name Synonyms
      Secondary FlyBase IDs
        References (8)