FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ty1
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General Information
Symbol
Dmel\ty1
Species
D. melanogaster
Name
FlyBase ID
FBal0017321
Feature type
allele
Associated gene
ty
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Bristles small. Body small. Eclosion delayed. Viability excellent. Female sterile; eggs rarely found and only in a few ovarioles (Perrimon and Gans, 1983). Yolk formation in oocytes inhibited (King and Burnett, 1957). Follicular cells form abnormal derivatives of endoplasmic reticulum and migrate abnormally or form excess of normal endoplasmic reticulum derivative (King and Vanoucek, 1960; Falk and King, 1964). ty ovaries in ty+ host develop autonomously (King and Bodenstein, 1965). The heteroallelic combination ty/ty2 exhibits the visible phenotypes described for ty homozygotes (Schalet, 1986), and, in addition, may show a reduction in thoracic hairs and abnormally-shaped rough eyes; viability severely reduced in some cultures. RK2.

        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        NOT suppressed by
        Statement
        Reference

        ty1 has phenotype, non-suppressible by su(Hw)2

        (Lindsley and Grell, 1968)
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer

        Bridges, 1st Nov. 1925.

        Comments
        Comments

        Pole cell transplantation shows that the ty1 mutation acts in the germ cells.

        (DiMario and Hennen, 1982)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        ty
        (DiMario and Hennen, 1982)
        ty1
        Name Synonyms
        Secondary FlyBase IDs
          References (2)