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General Information
Symbol
Dmel\Ubxabx-CAC4
Species
D. melanogaster
Name
FlyBase ID
FBal0017515
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
abxCAC4
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology

Polytene chromosomes normal.

Nature of the lesion
Statement
Reference

Cis-regulatory mutation.

Deletion of Ubx DNA and insertion of hobo in the abx regulatory region.

Deletion within an intron of the Ubx transcription unit, together with insertion of a hobo at the site of the deletion.

Insertion of a hobo and deletion of Ubx sequences.

Deletion in the abx regulatory region of Ubx.

hobo insertion and a deletion from position -80 and -66kb of the Ubx locus.

Insertion components
H{}Ubxabx-CAC4
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Increases the frequency of the trx bithorax-variegated phenotype (partial transformation of T3 to T2, mostly in the anterior compartment) in heterozygous combination with Df(3R)red-P52.

Transformation of parasegment 5 structures to parasegment 4. Adults display transformation of anterior haltere to anterior wing.

Halteres are transformed to wings and are 15-30% of wing size, dorsal tissue of T3 is incompletely transformed to metanotum, hypopleural plates are incompletely transformed to sternopleural plates, 8-10 hypopleural bristles are still present and the anterior third leg displays a strong transformation to anterior second leg, as seen by the bristle pattern.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
Statement
Reference

Ubxabx-CAC4 has phenotype, enhanceable by ash128

Ubxabx-CAC4 has phenotype, enhanceable by ash218

Additional Comments
Genetic Interactions
Statement
Reference

Double heterozygotes with ash128 exhibit haltere to wing transformation and third to second leg transformation. Double heterozygotes with ash218 exhibit haltere to wing transformation.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
References (8)