FlyBase Allele Report: Dmel\Ubx[bx-34eprv]

General Information

Symbol

Dmel\Ubx^bx-34eprv

Species

D. melanogaster

Name

bx-34e partial revertant

FlyBase ID

FBal0017522

Feature type

allele

Associated gene

Dmel\Ubx

Associated Insertion(s)

Carried in Construct

Also Known As

bx^34e-prv, bx^34eprv

Key Links

Allele class

Mutagen

X ray

Nature of the Allele

Allele class

Mutagen

X ray

(Peifer and Bender, 1986)

Progenitor genotype

Ubx^bx-34e

(Castelli-Gair and Garcia-Bellido, 1990, Little et al., 1990, Peifer and Bender, 1986)

Cytology

Polytene chromosomes normal.

(Castelli-Gair and Garcia-Bellido, 1990)

Description

Cis-regulatory mutation.

(LaJeunesse and Shearn, 1995)

Excision of gypsy element deleting 9.5kb of Ubx DNA.

(Castelli-Gair and Garcia-Bellido, 1990)

Deletion of approximately 10kb DNA within an intron of the Ubx transcription unit.

(Little et al., 1990)

Deletion of DNA.

(Micol et al., 1990)

Deletion from position -66.5 to -57kb of the Ubx locus.

(Peifer and Bender, 1986)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

adult metathoracic segment anterior compartment

(Castelli-Gair and Garcia-Bellido, 1990)

haltere

(LaJeunesse and Shearn, 1995, Peifer and Bender, 1986)

katepimeron

(Peifer and Bender, 1986)

metathoracic leg

(LaJeunesse and Shearn, 1995)

metathoracic leg | anterior

(Peifer and Bender, 1986)

metathoracic segment | dorsal

(Peifer and Bender, 1986)

Detailed Description

Statement

Reference

Partial revertant. Increases the frequency of the trx bithorax-variegated phenotype (partial transformation of T3 to T2, mostly in the anterior compartment) in heterozygous combination with Df(3R)red-P52.

(Castelli-Gair and Garcia-Bellido, 1990)

Partial revertant.

(Little et al., 1990)

Halteres are transformed to wings and are 3-15% of wing size, dorsal tissue of T3 is incompletely transformed to metanotum, hypopleural plates are incompletely transformed to sternopleural plates, 0-2 hypopleural bristles are still present and the anterior third leg displays a moderate transformation to anterior second leg, as seen by the bristle pattern.

(Peifer and Bender, 1986)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

Ubx^bx-34eprv has phenotype, enhanceable by ash1²⁸

(LaJeunesse and Shearn, 1995)

Ubx^bx-34eprv has phenotype, enhanceable by ash2¹⁸

(LaJeunesse and Shearn, 1995)

Additional Comments

Genetic Interactions

Statement

Reference

Double heterozygotes with ash1²⁸ exhibit haltere to wing transformation and third to second leg transformation. Double heterozygotes for ash2¹⁸ at 20^oC or 27^oC do not show homeotic transformations.

(LaJeunesse and Shearn, 1995)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Lewis.

(Peifer and Bender, 1986)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

Ubx^bx-34eprv

bx34^e-prv

(Castelli-Gair, 1998)

bx^34e-prv

(Castelli-Gair and Garcia-Bellido, 1990, Little et al., 1990, Peifer and Bender, 1986)

bx^34eprv

(LaJeunesse and Shearn, 1995, Micol et al., 1990)

bx^erv-7420

(LaJeunesse and Shearn, 1995)

Name Synonyms

bx-34e partial revertant

(Peifer and Bender, 1986)

Secondary FlyBase IDs

References (6)

Report Sections

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