FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\UbxCbx-2
Open Close
General Information
Symbol
Dmel\UbxCbx-2
Species
D. melanogaster
Name
FlyBase ID
FBal0017564
Feature type
allele
Associated gene
Dmel\Ubx
Associated Insertion(s)
Carried in Construct
Also Known As
Cbx2
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Caused by aberration
    In(3R)Cbx2
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        The mesothorax phenotype is reduced in combination with RpII215Ubl or RpS174. The dominant wing phenotype is 100% penetrant, occurring in the posterior compartment and variably in the anterior compartment. UbxCbx-2/Ubx195 transheterozygotes show transformation of T3 towards T2, and A1a towards T3a.

        (Gonzalez-Gaitan et al., 1990)

        Hemizygotes display ventral setal belt on the first abdominal segment is intermediate between the normal third thoracic belt and the normal first abdominal belts.

        (Bender et al., 1985)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Other
        Statement
        Reference

        UbxCbx-2, ph-d2 has wing phenotype

        (Dura et al., 1985)

        UbxCbx-2, ph-d2 has scutum phenotype

        (Dura et al., 1985)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Semi-lethal in combination with ph-d2. Escapers show complete transformation of wing to haltere and a marked reduction of the mesonotum.

        (Dura et al., 1985)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer

        Kreber.

        (Lindsley and Zimm, 1992)
        Comments
        Comments

        The Cbx mesothorax phenotype is reduced in a number of Cbx mutations in combination with RpII215Ubl. This reduction of the Cbx phenotype follows the order: UbxCbx-Hm > UbxCbx-2RM = UbxCbx-2 = UbxCbx-M1 > UbxCbx-1RM = UbxCbx-1 = UbxCbx-3 = UbxCbx-Twt. The Cbx mesothorax phenotype is reduced in a number of Cbx mutations in combination with RpS174. This reduction of the Cbx phenotype follows the order: UbxCbx-2RM > UbxCbx-2 = UbxCbx-M1 > UbxCbx-1 = UbxCbx-1RM.

        (Gonzalez-Gaitan et al., 1990)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        Cbx2
        (Duncan, 2002, Gonzalez-Gaitan et al., 1990, Lipshitz et al., 1987, Bender et al., 1985, Dura et al., 1985, Bender et al., 1983)
        UbxCbx-2
        Name Synonyms
        Secondary FlyBase IDs
          References (7)