Polytene chromosomes normal.
ph-d2/Hsc70-4195 mutant flies exhibit a higher than wild-type average number of legs with sex combs, with a statistically significant average of 4.0 legs with sex combs, compared to 2.6 in ph-d2/+ heterozygotes.
ph-d2 ph-p2 homozygotes do not show a gap in the fourth wing vein at 25 or 29oC. 100% of ph-d2 ph-p2/Y ; en54/+ flies have a gap in the fourth wing vein at 29oC. 100% of ph-d2 ph-p2/Y ; en4/+ flies have a gap in the fourth wing vein at 29oC.
The extra sex combs phenotype of ph-d2 heterozygotes is dominantly enhanced by Df(2L)esc-P2-0, Df(2L)prd1.7, Df(2L)esc10, salm1, Df(2L)H20, Df(2L)TW3, Df(2L)TW201, Df(2R)CA53, Df(2R)cn83c, Df(3L)fz-GF3b, Df(3L)fz-GS1a and Df(3L)fz-CAL5. Lethal in heterozygous combination with Df(2L)Prl.
The abdominal transformations are enhanced by Df(3R)P9, and suppressed by Dp(3;3)P5. The leg transformations are suppressed by Dp(3;3)D1, and enhanced by Df(3R)Scr. Dominant enhancer of Pc3. Interacts with esc20 and Pcl1. Semi-lethal in combination with UbxCbx-2. Escapers show complete transformation of wing to haltere and a marked reduction of the mesonotum. Lethal in combination with Abd-BUab-1. The third abdominal segment is transformed towards segment five or six in males also carrying Abd-BMcp-1. Enhances the ScrMsc, AntpB and AntpScx phenotypes. Does not interact with AntpHu.