FlyBase Aberration Report: Dmel\Df(2R)CA53

General Information

Symbol

Df(2R)CA53

Species

D. melanogaster

Name

FlyBase ID

FBab0001947

Feature type

chromosomal_deletion

Also Known As

CA53

Computed Breakpoints include

43E7-43E18;44B6

Features within 43E7--44B6

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

gamma ray

irradiation

(Warren et al., 1996)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Pauli et al., 1995, Landecker et al., 1994)

Breakpoints

43E6;44B5-44B9

(Landecker et al., 1994)

43E6;44B6

(Pauli et al., 1995)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

tor << bk1 << Gapdh1 << sax << bk2

Genetic mapping information

Comments

Breakpoint(s) molecularly mapped

(Howells, 1989)

Comments on Cytology

Left limit of break 1 from non-inclusion of tor (FBrf0045941) Right limit of break 1 from inclusion of Gapdh1 (FBrf0097723) Limits of break 2 from polytene analysis (FBrf0080317)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

(Warren et al., 1996)

CSN4

(Oron et al., 2002, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Cul1

(Ou et al., 2002, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Gapdh1

(Warren et al., 1996)

rnh1

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

sax

(Nellen et al., 1994)

Partially deleted / disrupted

Molecular Data

Completely deleted

mRpL52

(Marygold et al., 2007)

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
In these cases, there will be no "Export to Hitlist" button to the left.

Related Comments

Phenotypic Data

In combination with other aberrations

Has no effect on the frequency of X-Y chromosome nondisjunction seen in Df(1)X-1-53B males.

(McKee et al., 2000)

Df(2R)cn83c/Df(2R)CA53 embryos are usually wild-type, but sometimes have segmentation defects and denticles in the third thoracic segment that resemble abdominal denticles. Df(2R)CA53/Df(2R)cn83c ; Scm¹/+ embryos lack terminal structures and are U-shaped. Denticle belts of the 3rd to 7th abdominal segments are transformed posteriorly.

(Landecker et al., 1994)

NOT in combination with other aberrations

Flies heterozygous for the deletion do not show a Minute bristle phenotype.

(Marygold et al., 2007)

The Df(2R)CA53 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion).

(Mason et al., 2004)

Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2.

(Pauli et al., 1995)

1-3% of male flies carrying Df(2R)CA53 have extra sex combs.

(Landecker et al., 1994)

Ocelli small in heterozygotes.

Stocks (2)

3364

107008

Notes on Origin

Discoverer

Durrant.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

CA53

(Hirose et al., 2001, Yamaguchi et al., 2001, Yamaguchi et al., 1999)

Df(2)CA53

(Rawlings et al., 2004)

Df(2L)CA53

(Tearle and Nusslein-Volhard, 1987)

Df(2R)CA53

(Chartier et al., 2015, Beumer et al., 2008, Benoit et al., 2005, Myllykangas et al., 2005, Sevrioukov et al., 2005)

Df(2R)ca53

(Filippov et al., 2000)

Df3364

(Elmore and Smith, 2001)

Name Synonyms

Secondary FlyBase IDs

References (29)

Report Sections

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