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General Information
Symbol
Dmel\Scm1
Species
D. melanogaster
Name
FlyBase ID
FBal0015265
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Shows no dominant effect on telomeric Position Effect Variegation (PEV) in stocks carrying a variegating w+mW.hs allele at the telomeres of the second and third chromosomes.

Homozygous embryos show posteriorly directed transformations; A1 resembles A2 and A2-7 transformed into more posterior segments, head and thorax normal. Pcl1 Scm1 double homozygotes exhibit transformation of all segments toward A8; Keilin's organs retained in thoracic segments; head involution does not occur; prominent abdominal denticle band seen on dorsal surface of head. Homozygous embryos derived from transplanted homozygous maternal germ-cell precursors display A8 morphology in all thoracic and abdominal segments; head seems to resemble that of Pcl1 Scm1 double homozygotes produced by heterozygous mothers; heterozygous adults from homozygous oocytes show patchy transformations of A4 to A5 and of A6 and A7 to A8; similar transformation infrequently seen in heterozygous offspring of heterozygous mothers.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Df(2L)TW3/Df(2L)TW201; Scm1/+ embryos have severe head defects including almost complete loss of the cephalopharyngeal skeleton, show partial transformation of the 1st abdominal segment to a more posterior segment, and show transformation of the 6th and 7th abdominal segments towards the 8th abdominal segment. Df(2R)CA53/Df(2R)cn83c; Scm1/+ embryos lack terminal structures and are U-shaped. Denticle belts of the 3rd to 7th abdominal segments are transformed posteriorly.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (5)