Open Close
General Information
Symbol
Dmel\vas6
Species
D. melanogaster
Name
FlyBase ID
FBal0017850
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
vasQ6
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

G15073377A

Reported nucleotide change:

G?A

Amino acid change:

V465M | vas-PA; V465M | vas-PB; V465M | vas-PC

Reported amino acid change:

V465M

Comment:

Lasko, 2000.2.7, personal communication

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: V465M.

Nucleotide substitution of ATG for GTG, (amino acid replacement of V by M) in the 425 amino stretch that is highly similar among DEAD-box proteins.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

46% of eggs laid by vas7/vas6 females have a micropyle at the posterior end of the egg. Occasionally, vas7/vas6 egg chambers containing two oocytes are seen. These are often adjacent to egg chambers that lack an oocyte. 100% of eggs laid by vas1/vas6 females appear wild-type.

Absence of posterior pole plasm, polar granules and pole cells.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Strong allele of vas. Cytoplasmic transplantation of wild type plasm into the abdominal region restores normal abdominal development.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
References (8)