FlyBase Allele Report: Dmel\SP[g.Yp1.hs]

General Information

Symbol

Dmel\SP^g.Yp1.hs

Species

D. melanogaster

Name

FlyBase ID

FBal0028725

Feature type

allele

Associated gene

Dmel\SP

Associated Insertion(s)

Carried in Construct

P{SP^g.Yp1.hs}

Also Known As

YPhsSPg

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Aigaki et al., 1991)

Progenitor genotype

SP^c.Yp1.hs

(Aigaki et al., 1991)

Carried in construct

P{SP^g.Yp1.hs}

Cytology

Description

Construct: 140bp AvaII-SalI fragment of Acp70A cDNA sequences is replaced with a 460bp AvaII-SalI fragment of genomic DNA containing two thirds of the coding region interrupted by a 65bp intron.

(Aigaki et al., 1991)

Allele components

Component

Use(s)

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal courtship behavior | female

(Aigaki et al., 1991)

abnormal feeding behavior | female limited

(Carvalho et al., 2006)

abnormal mating behavior | virgin female limited

(Haussmann et al., 2013)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of SP^g.Yp1.hs reduces the receptivity and increases oviposition in virgin females.

(Haussmann et al., 2013)

Females bearing Acp70A^g.Yp1.hs exhibit a constitutively increased feeding rate that is not further elevated by mating.

(Carvalho et al., 2006)

In Acp70A^g.Yp1.hs virgin females a prolonged stimulation of oviposition corresponding to about 70% of the full wild-type male induced response is seen.

(Xue and Noll, 2000)

Females with and without eggs extrude their ovipositor towards courting males, this rejection behaviour is ineffective at suppressing wild type male courtship. Half of females with eggs can suppress male courtship and females without eggs fail to. dnc^M11 and para^sbl-1 males show increased courtship with Acp70A^g.Yp1.hs females than wild type males.

(Fuyama and Ueyama, 1997)

Constitutive expression of Acp70A under the control of the Yp1 enhancer produced constitutive rejection behaviour in the presence of courting males and enhanced ovulation.

(Aigaki et al., 1991)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT suppressed by

Statement

Reference

SP^g.Yp1.hs has abnormal mating behavior | virgin female limited phenotype, non-suppressible by Df(1)JC70/Df(1)Exel6234

(Haussmann et al., 2013)

Enhancer of

Statement

Reference

SP^g.Yp1.hs is an enhancer of short lived | female phenotype of otu⁶

(Ueyama and Fuyama, 2003)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Expression of SP^g.Yp1.hs in Df(1)JC70/Df(1)Exel6234 mutant females fails to reduce receptivity, but results in a small but significant increase in oviposition.

(Haussmann et al., 2013)

otu⁶ homozygous females that also express Acp70A^g.Yp1.hs have an extremely short life span, that is significantly lower than that of otu⁶ single homozygous females.

(Ueyama and Fuyama, 2003)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

4365