FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Dll+m312
Open Close
General Information
Symbol
Dmel\Dll+m312
Species
D. melanogaster
Name
FlyBase ID
FBal0029042
Feature type
allele
Associated gene
Dmel\Dll
Associated Insertion(s)
Carried in Construct
P{Dll+m312}
Key Links
Transgenic product class
wild_type
(Vachon et al., 1992)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Vachon et al., 1992)
Mutagen
in vitro construct
(Vachon et al., 1992)
Progenitor genotype
Carried in construct
P{Dll+m312}
Cytology
Description

Dll cDNA minigene expressed from a Dll promoter including 17.5 kb of 5' flanking region, encompassing both the early (304) and late (215) enhancers.

(Vachon et al., 1992)
Allele components
Component
Use(s)
Regulatory region(s)
Dll
Encoded product / tool
Dll
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Confers significant phenotypic rescue of Dll null mutants Keilin's organs.

      (Vachon et al., 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Dll+m312 partially rescues Df(2R)ED4065/Dll17

      (Galindo et al., 2011)

      Dll+m312 partially rescues Dllunspecified

      (Vachon et al., 1992)
      Comments

      Some Dll17/Df(2R)ED4065 animals carrying Dll+m312 survive until the pharate adult stage. These animals show severe truncation and malformation of the medial and distal leg segments. The distal tibia and tarsal regions are absent, the femur is shortened and the trochanter is deformed. The bristles on the femur lack bracts, in contrast to wild type. Mechanosensory bristles of the wing margin are missing.

      (Galindo et al., 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Dll+m312
      Dll312
      (Galindo et al., 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)