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General Information
Symbol
Dmel\Polr2BZ43
Species
D. melanogaster
Name
FlyBase ID
FBal0030142
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Nucleotide change:

G14128967A

Reported nucleotide change:
Amino acid change:

R940H | RpII140-PA; R940H | RpII140-PB

Reported amino acid change:
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: R940H. Nucleotide substitution: G3678A.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

25.2% of heterozygous males show anterior transformation of segment A6 to A5.

Exhibits the Ubx effect: heterozygotes partially transform the capitellum of the haltere into the wing blade.

Ubx effect: transformation of capitellum to wing. Temperature sensitive period is from the middle of the third larval instar to the middle of the pupal stage.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

Polr2BZ43 has visible | dominant | homeotic | male phenotype, enhanceable by scf1/scf[+]

Phenotype Manifest In
Enhanced by
Statement
Reference

Polr2BZ43 has adult abdominal segment 6 | male phenotype, enhanceable by scf1/scf[+]

Additional Comments
Genetic Interactions
Statement
Reference

scf1/+ significantly enhances the penetrance of the A6 to A5 transformation phenotype that is seen in RpII140Z43/+ males.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Polr2BZ43
RpII140Z43
Name Synonyms
Secondary FlyBase IDs
    References (4)