FB2026_02 , released June 18, 2026
Allele: Dmel\UbxMX6
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General Information
Symbol
Dmel\UbxMX6
Species
D. melanogaster
Name
FlyBase ID
FBal0030344
Feature type
allele
Associated gene
Dmel\Ubx
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
    Nature of the Allele
    Allele class

    amorphic allele - genetic evidence

    (Gould and White, 1992, Martinez-Laborda et al., 1992)
    Mutagen
    Progenitor genotype
    Cytology
    Description

    3.4kb deletion that includes the EcoRI/HindIII fragment harbouring the two Ubx transcription start sites.

    (Martinez-Laborda et al., 1992)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        The UbxMX6 chromosome is also deficient for abd-A function: the homozygous mutant chromosome has the same phenotype as Df(3R)Ubx109. UbxMX6/Df(3R)bxd100 is wild type for abd-A and shows the null Ubx phenotype. In clonal analysis UbxMX6 tissue looks as for pre-existing Ubx null alleles. Transheterozygous combinations with many different classes of Ubx mutation, and wild type indicate that Ubx195rx1 hyperactivates the homologous Ubx gene. Effect is pairing-dependent. Mutation has strong positive effect on transvection, which, unlike other cases of transvection in Ubx, is not zeste-dependent.

        (Martinez-Laborda et al., 1992)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Postembryonic neuroblast clones in the anterior or posterior thorax which are mutant for both abd-AM1 UbxMX6 are normal in size.

        (Bello et al., 2003)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        Comments
        Comments

        The UbxMX6 chromosome is also deficient for abd-A function: the homozygous mutant chromosome has the same phenotype as Df(3R)Ubx109.

        (Martinez-Laborda et al., 1992)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        UbxMX6
        (Moris-Sanz et al., 2015, Estacio-Gómez et al., 2013)
        UbxMx6
        (Duncan, 2002)
        Name Synonyms
        Secondary FlyBase IDs
          References (7)