FB2026_03 , released September 17, 2026
Allele: Dmel\achb.PP
Open Close
General Information
Symbol
Dmel\achb.PP
Species
D. melanogaster
Name
hunchback promoter construct of Parkhurst
FlyBase ID
FBal0030457
Feature type
allele
Associated gene
Dmel\ac
Associated Insertion(s)
Carried in Construct
P{hb-ac}
Key Links
Transgenic product class
wild_type
(Parkhurst et al., 1990)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Parkhurst et al., 1990)
Mutagen
in vitro construct
(Parkhurst et al., 1993, Parkhurst et al., 1990)
Progenitor genotype
Carried in construct
P{hb-ac}
Cytology
Description

The hb promoter drives expression of the ac coding region.

(Parkhurst et al., 1990)
Allele components
Component
Use(s)
Regulatory region(s)
hb
Encoded product / tool
ac
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      immunolocalization
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 5 -- 12
      organism | 50-100% egg length
      (Parkhurst et al., 1990)
      Additional Information
      Statement
      Reference

      ac protein isexpressed ectopically in the hb domain (anterior 45% of the embryo) andis first detected in nuclear cycle 11/12.

      (Parkhurst et al., 1990)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      No effect on viability.

      (Parkhurst et al., 1990)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      achb.PP is a suppressor of lethal | female phenotype of hryhb.PP

      (Parkhurst et al., 1993)
      Other
      Statement
      Reference

      achb.PP, hryhb.PP has viable | female phenotype

      (Parkhurst et al., 1993)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Single copy rescues the female lethality of hhb.PP.

      (Parkhurst et al., 1993)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      achb.PP
      Name Synonyms
      hunchback promoter construct of Parkhurst
      (Parkhurst et al., 1990)
      Secondary FlyBase IDs
        References (2)