FB2026_02 , released June 18, 2026
Allele: Dmel\ana8
Open Close
General Information
Symbol
Dmel\ana8
Species
D. melanogaster
Name
FlyBase ID
FBal0030492
Feature type
allele
Associated gene
Dmel\ana
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Datta, 1995)

loss of function allele

(Ebens et al., 1993)
Mutagen
Delta2-3 transposase
(Ebens et al., 1993)
Progenitor genotype
ana1
(Park et al., 1997, Ebens et al., 1993)
Cytology
Description

Imprecise excision of the P{lacZ} element in ana1, resulting in a deletion of ana DNA.

(Park et al., 1997)

Dysgenesis-induced excision removing exons 2, 3 and 4.

(Ebens et al., 1993)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous adults have no gross morphological abnormalities. These adults do not live for long after eclosion under crowded conditions in competition with wild-type siblings.

      (Park et al., 1997)

      Premature proliferation of optic lobe and thoracic neuroblast populations.

      (Datta, 1995)

      Similar to ana1.

      (Ebens et al., 1993)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT suppressed by
      Statement
      Reference

      ana8 has increased occurrence of cell division | third instar larval stage phenotype, non-suppressible by trolsd

      (Datta, 1995)
      Phenotype Manifest In
      NOT suppressed by
      Statement
      Reference

      ana8 has thoracic neuroblast | third instar larval stage phenotype, non-suppressible by trolsd

      (Datta, 1995)

      ana8 has adult optic lobe | third instar larval stage phenotype, non-suppressible by trolsd

      (Datta, 1995)

      ana8 has neuroblast | third instar larval stage phenotype, non-suppressible by trolsd

      (Datta, 1995)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      trolsd/ana8 double mutants have a proliferation phenotype indistinguishable from ana8 homozygotes (premature proliferation of optic lobe and thoracic neuroblast populations), individuals do not survive to adulthood (polyphasic lethality).

      Premature proliferation of optic lobe and thoracic neuroblast populations. trolsd/ana8 double mutant have a proliferation phenotype indistinguishable from ana8 homozygotes, individuals do not survive to adulthood (polyphasic lethality).

      (Datta, 1995)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ana8
      Name Synonyms
      Secondary FlyBase IDs
        References (3)