FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\btlH82Δ11
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General Information
Symbol
Dmel\btlH82Δ11
Species
D. melanogaster
Name
FlyBase ID
FBal0030664
Feature type
allele
Associated gene
Dmel\btl
Associated Insertion(s)
P{5'lwB}btlH82Δ11
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Cela and Llimargas, 2006, Myat et al., 2005, Klambt et al., 1992)
Mutagen
Delta2-3 transposase
(Klambt et al., 1992)
Progenitor genotype
P{lwB}H82
(Klambt et al., 1992)
Associated Insertion(s)
P{5'lwB}btlH82Δ11
Cytology
Description

Partial excision of P{lwB}H82. Deletion removes neither Ecol\lacZ nor w coding regions, but deletes genomic DNA 3' of the site of insertion towards, but not including, the start site of btl transcription.

(Klambt et al., 1992)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      btlH82Δ11 embryos show reduced tracheal branch outgrowth compared to wild-type embryos but show no defects in branch integrity.

      (Cela and Llimargas, 2006)

      In btlH82Δ11 embryos, the migration of all primary tracheal branches is affected. Some branches, such as the dorsal trunk, ganglionic and visceral branches initiate but do not complete their migration. In btl95/btlH82Δ11 embryos, migration of all primary tracheal branches is affected to varying degrees.

      (Myat et al., 2005)

      Tracheal pits form, but tracheal cells undergo only limited migration.

      (Klambt et al., 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Phenotype of homozygote less severe than phenotype of heterozygote with Df(3L)fz-GF3b or Df(3L)fz-GS1a. The btl alleles form a phenotypic series with respect to the tracheal phenotype. In decreasing order of severity, btlLG18 = btlLG19 > btlH82Δ3 > btlH82Δ11 > btl6-81Δ1.

      (Klambt et al., 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      btlH82Δ11
      (Cela and Llimargas, 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)